D&C 45

 As the saints were wondering much like the ancient disciples concerning the second coming of the Savior and the signs of His coming, we are told - 

"...in that day shall be heard of wars and rumors of wars, and the whole earth shall be in commotion, and men’s hearts shall fail them, and they shall say that Christ delayeth his coming until the end of the earth.

27 And the love of men shall wax cold, and iniquity shall abound.

28 And when the times of the Gentiles is come in, a light shall break forth among them that sit in darkness, and it shall be the fulness of my gospel;

29 But they receive it not; for they perceive not the light, and they turn their hearts from me because of the precepts of men.

30 And in that generation shall the times of the Gentiles be fulfilled.

31 And there shall be men standing in that generation, that shall not pass until they shall see an overflowing scourge; for a desolating sickness shall cover the land.

32 But my disciples shall stand in holy places, and shall not be moved; but among the wicked, men shall lift up their voices and curse God and die."  (Doctrine and Covenants 45:26–32)

Though I believe the desolating sickness to be wickedness, it could also be referencing a great pandemic.